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Once dosage goes up, safety naturally becomes the next concern

A RCT verified that patients treated with NAC had higher GSH levels in PBMCs, along with upregulated Foxp3 expression and suppressed mTOR activity (lower expression of phosphorylated S6 protein), which ultimately resulted in lower anti-dsDNA antibody titers and SLEDAI scores (Clinicaltrials.gov: NCT00775476) (255)

Sharma, 2021

This review addresses the research question, Can incorporating fermented foods in the maternal diet produce positive health outcomes in mothers and infants?. With this review, our objective is not to narrate the existing literature in the adult population but to contribute to a better understanding of the areas within maternal fermented food intake and infant gut, immune and brain outcomes where there is a knowledge gap

Individual responses vary based on genetics, baseline body composition, adherence to protocol, and lifestyle factors

Titov et al