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Occasionally the picture of Hashimoto's thyroiditis blends rather imperceptibly into that of thyrotoxicosis, and some patients have symptoms of mild thyrotoxicosis, but then develop typical Hashimoto's thyroiditis

Wang et al., 2014b

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Effect of metformin on neurodegenerative disease among elderly adult US veterans with type 2 diabetes mellitus

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It helps neutralize free radicals and binds to toxins to make them water-soluble for excretion, though its effectiveness depends heavily on the delivery method used