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This is an observed phenomenon where the peptides ability to accelerate cell turnover brings underlying congestion (such as microcomedones or trapped sebum) to the surface more quickly

Research suggests GHK-Cu is active at quite low concentrations - as little as 0.001% in some studies

rs12325817) of the PEMT gene, which may affect the expression and/or activity of the PEMT enzyme, is thought to increase the susceptibility to choline deficiency-induced organ dysfunction (18)

Also, IF decrease plasma levels of ceramide C17, C22, and C24 sphingomyelin, as well as C20, C22, C24, and C24:1 dihydrosphingomyelin ( coactivator 1 (PGC-1), a transcription factor of mitochondria function, in neurons (Wilhelmi de Toledo et al., 2020

Well take time to understand your concerns, go over whats possible, and help you decide if now is the right time.

Liu AW, Gillis JE, Sumpter TL, Kaplan DH (2023) Neuroimmune interactions in atopic and allergic contact dermatitis