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The authors explain: The faster a reinforcing substance reaches the brain, the steeper the rise is in dopamine and the more addictive the product becomes. To achieve this speed, tobacco companies stripped tobacco leaves down to their molecular components, reconstituted them into uniform sheets and added ammonia to freebase the nicotine, making it absorb more efficiently through the lungs
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However, the study concluded that more research should be done in the area as they found an unknown risk of bias in the studies included [66] Another systematic review analyzed pharmacist intervention in smoking cessation and alcohol and weight interventions
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